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便携式小动物超声

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便携式小动物超声设备,它是专为实验小动物开发的高频高分辨率小动物超声成像系统,为研究者提供无创连续分析,高分辨率图像质量和组织结构和血流速度的定量分析。通过专门为小鼠和大鼠设计的硬件和软件,以及优化的人体工学操作设计,为研究人员在心血管研究,基因表达模式分析,肿瘤研究和药物开发等方面提供具有成本效益的应用工具。

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文献:

序号文献名(英文)期刊发表日期影响因子发表单位
1α-myosin heavy chain lactylation maintains sarcomeric structure and function and alleviates the development of heart failureCELL RESEARCH2023.0744.1中国医科大学附属第一医院心血管内科
2BAF155 promotes cardiac hypertrophy and fibrosis
through inhibition of WWP2-mediated PARP1
ubiquitination
Cell Discovery2023.0538.079中国医科大学附属第一医院心血管内科
3Ultrasound-triggered microbubble destruction enhances the radiosensitivity of glioblastoma by inhibiting PGRMC1-mediated autophagy in vitro and in vivo Military Medical Research2022.0234.915第三军医大学新桥医院
4Treatment of infarcted heart tissue via the capture and local delivery of circulating exosomes through antibody-conjugated magnetic nanoparticles Nature Biomedical Engineering2020.1129.234第四军医大学西京医院
5Drug-loaded balloon with built-in NIR controlled tip-separable microneedles for long-effective arteriosclerosis treatmentBioactive Materials2023.0518.9南昌大学转化医学研究所国家生物工程药物及技术工程研究中心
6Phosphoglycerate dehydrogenase activates PKM2 to phosphorylate histone H3T11 and attenuate cellular senescenceNature Communications2023.0317.694湖北大学生命科学学院
7Engineered neutrophil apoptotic bodies ameliorate myocardial infarction by promoting macrophage efferocytosis and inflammation resolutionBioactive Materials 2021.0816.874第四军医大学
8Drug-loaded balloon with built-in NIR controlled tip-separable microneedles for long-effective arteriosclerosis treatmentBioactive Materials2022.1216.874南昌大学第二附属
9Upconversion nanoparticles regulated drug & gas dual-effective nanoplatform for the targeting cooperated therapy of thrombus and anticoagulationBioactive Materials2022.0316.874南昌大学第二附属
10V1-Cal hydrogelation enhances its effects on ventricular remodeling reduction and cardiac function improvement post myocardial infarctionChemical Engineering Journal2022.0116.744安徽医科大学附属第二医院

CD44 connects autophagy decline and ageing in the vascular endotheliumNature Communications2023.09.0816.6河南工业大学
111-Deoxynojirimycin promotes cardiac function and rescues mitochondrial cristae in mitochondrial hypertrophic cardiomyopathyJOURNAL OF CLINICAL INVESTIGATION2023.0715.9浙江大学生命科学学院
12L‐Arginine‐Loaded Gold Nanocages Ameliorate Myocardial Ischemia/Reperfusion Injury by Promoting Nitric Oxide Production and Maintaining Mitochondrial FunctionAdvanced Science2023.07.1415.1北京大学基础医学院心血管科学研究所
13Alleviating experimental pulmonary hypertension via co-delivering FoxO1 stimulus and apoptosis activator to hyperproliferating pulmonary arteriesActa Pharmaceutica Sinica B2023.0614.5中国药科大学药学院
14Donor MSCs release apoptotic bodies to improve myocardial infarction via autophagy regulation in recipient cellsAutophagy2020.0113.391第四军医大学西京医院
15iNOS contributes to heart failure with preserved ejection fraction through mitochondrial dysfunction and Akt S-nitrosylationJournal of Advanced Research2023.0112.822重庆医科大学第一附属医院
16Fatty acid-binding protein 5 aggravates pulmonary artery fibrosis in pulmonary hypertension secondary to left heart disease via activating wnt/β-catenin pathwayJournal of Advanced Research2021.1112.822武汉大学中南医院
17iNOS aggravates pressure overload-induced cardiac dysfunction via activation of the cytosolic-mtDNA-mediated cGAS-STING pathwayTheranostics2023.0712.4重庆医科大学第一附属医院心内科
18MMP 9-instructed assembly of bFGF nanofibers in ischemic myocardium to promote heart repairTheranostics2022.111.6安徽医科大学第二附属医院
19Automatic Respiratory Gating Hepatic DCEUS-based Dual-phase Multi-parametric Functional Perfusion Imaging using a Derivative Principal Component AnalysisTheranostics2019.0811.6西安交通大学生命科学与技术学院生物医学工程系,
20Diminished α7 nicotinic acetylcholine receptor (α7nAChR) rescues amyloid-β induced atrial remodeling by oxi-CaMKII/MAPK/AP-1 axis-mediated mitochondrial oxidative stressRedox Biology2023.0110.787北方战区总医院
21Epigallocatechin-3-gallate pretreatment alleviates doxorubicin-induced
ferroptosis and cardiotoxicity by upregulating AMPK α 2 and activating
adaptive autophagy
Redox Biology2021.1110.787南昌大学第一附属医院
22Hepatic Acat2 overexpression promotes systemic cholesterol metabolism and adipose lipid metabolism in miceDiabetologia2022.1110.46苏州大学苏州医学院
23Nucleosome assembly protein 1 like 1 (NAP1L1) promotes cardiac fibrosis by inhibiting YAP1 ubiquitination and degradationMedComm (2020)2023.08.159.9哈尔滨医科大学药学院
24Fasting promotes acute hypoxic adaptation by suppressing mTOR-mediated pathwaysCell Death & Disease2021.119.685空军医科大学
25Legumain is a predictor of all-cause mortality and potential therapeutic target in acute myocardial infarctionCell Death & Disease2020.119.685中南大学湘雅二医院
26Echocardiographic assessment of Xenopus tropicalis heart regenerationCell and Bioscience2023.029.584暨南大学
27Long non-coding RNA KCND1 protects hearts from hypertrophy by targeting YBX1Cell Death & Disease2023.059上海工程技术大学前沿医学技术研究所
28Dapagliflozin reduces the vulnerability of rats with pulmonary arterial hypertension-induced right heart failure to ventricular arrhythmia by restoring calcium handlingCardiovascular Diabetology 2022.028.949武汉大学人民医院
29Human-Induced CD49a+ NK Cells Promote Fetal GrowthFrontiers in Immunology2022.028.786合肥中国科学技术大学
30The role of neutrophil elastase in aortic valve calcificationJournal of Translational Medicine2022.048.44重庆医科大学
31Sononeoperfusion effect by ultrasound and microbubble promotes nitric oxide release to alleviate hypoxia in a mouse MC38 tumor modelUltrason Sonochem2023.09.238.4第三军医大学新桥医院
32UGCG modulates heart hypertrophy through B4GalT5-mediated mitochondrial oxidative stress and the ERK signaling pathwayCELLULAR & MOLECULAR BIOLOGY LETTERS2023.09.018.3武汉大学人民医院老年科
33Novel Insights into the Cardioprotective Effects of Calcitriol in Myocardial InfarctionCells2022.057.666安徽医科大学基础医学院
34MicroRNA-145 Protects against Myocardial Ischemia Reperfusion Injury via CaMKII-Mediated Antiapoptotic and Anti-Inflammatory PathwaysOxidative Medicine and Cellular Longevity2019.097.31武汉大学人民医院
35Autologous Bioactive Compound Concentrated Growth Factor Ameliorates Fistula Healing of Anal Fistula in a Pig Model and Promotes Proliferation and Migration of Human Skin Fibroblasts via Regulating the MEK/ERK PathwayOxidative Medicine and Cellular Longevity2022.17.31杭州市第三人民医院
36The Roles of FGF21 and ALCAT1 in Aerobic Exercise-Induced Cardioprotection of Postmyocardial Infarction MiceOxidative Medicine and Cellular Longevity2021.117.31陕西师范大学体育学院
37Transcriptome-wide identification of altered RNA m6A profiles in cardiac tissue of rats with LPS-induced myocardial injuryFrontiers in Immunology2023.057.3中国医科大学附属盛京医院儿科
38Nitidine chloride induces cardiac hypertrophy in mice by targeting autophagy-related 4B cysteine peptidaseActa Pharmacologica Sinica2022.087.169哈尔滨医科大学药学院
39Multi-Modal Imaging Monitored M2 Macrophage Targeting Sono-Responsive Nanoparticles to Combat MRSA Deep InfectionsInternational Journal of Nanomedicine2022.097.033中南大学湘雅二院
40Ultrasound Assisted a Peroxisome Proliferator-Activated Receptor (PPAR)γ Agonist-Loaded Nanoparticle-Microbubble Complex to Attenuate Renal Interstitial FibrosisInternational Journal of Nanomedicine2020.17.033南京鼓楼医院
41Noise exposure and its relationship with postinfarction cardiac remodeling: implications for NLRP3 inflammasome activationBioengineered2022.036.832武汉大学人民医院
42Chronic Sigma 1 receptor activation alleviates right ventricular dysfunction secondary to pulmonary arterial hypertensionBioengineered2022.046.832武汉大学人民医院
43Protective effects of Dapagliflozin on the vulnerability of ventricular arrhythmia in rats with pulmonary artery hypertension induced by monocrotalineBioengineered2022.016.832武汉大学人民医院
44Ferrostatin-1 alleviates lipopolysaccharide-induced cardiac dysfunctionBioengineered2021.116.832武汉大学人民医院
45Optimal treatment occasion for ultrasound stimulated microbubbles in promoting gemcitabine delivery to VX2 tumorsDrug Delivery2022.096.819第三军医大学新桥医院
46Blackcurrant Improves Diabetic Cardiovascular Dysfunction by Reducing Inflammatory Cytokines in Type 2 Diabetes Mellitus MiceNutrients2021.116.706圆光大学韩医学专业研究生院
47Intermittent Fasting Improves High-Fat Diet-Induced Obesity Cardiomyopathy via Alleviating Lipid Deposition and Apoptosis and Decreasing m6A Methylation in the HeartNutrients2022.016.706清华大学体育学院
48Protective Effect of Vitis LABrusca Leaves Extract on Cardiovascular Dysfunction through HMGB1-TLR4-NFκB Signaling in Spontaneously Hypertensive RatsNutrients2020.16.706圆光大学汉邦心肾研究中心和东方医学专业研究生院
49Betulinic Acid Improves Cardiac-Renal Dysfunction Caused by Hypertrophy through Calcineurin-NFATc3 SignalingNutrients2021.096.706圆光大学东方医学学院和东方医学专业研究生院
50ATF3/SPI1/SLC31A1 Signaling Promotes Cuproptosis Induced by Advanced Glycosylation End Products in Diabetic Myocardial Injury International Journal of Molecular Sciences2023.016.208华中科技大学武汉同济医学院
51Exercise Training Alleviates Cardiac Fibrosis through Increasing Fibroblast Growth Factor 21 and Regulating TGF-β1-Smad2/3-MMP2/9 Signaling in Mice with Myocardial InfarctionInternational Journal of Molecular Sciences2021.116.208陕西师范大学体育学院
52Cas9/AAV9-Mediated Somatic Mutagenesis Uncovered the Cell-Autonomous Role of Sarcoplasmic/Endoplasmic Reticulum Calcium ATPase 2 in Murine Cardiomyocyte MaturationFrontiers in Cell and Developmental Biology2022.046.081北京大学医学部
53Astragaloside IV Ameliorates Isoprenaline-Induced Cardiac Fibrosis in Mice via Modulating Gut Microbiota and Fecal MetabolitesFrontiers in Cellular and Infection Microbiology2022.056.073重庆医科大学中医学院
54Zuogui Jiangtang Shuxin formula Ameliorates diabetic cardiomyopathy mice via modulating gut-heart axisFrontiers in Endocrinology2023.026.055湖南中医药大学附属第一医院
55Notoginsenoside R1 Regulates Ischemic Myocardial Lipid Metabolism by Activating the AKT/mTOR Signaling PathwayFrontiers in Pharmacology2022.065.988天津中医药大学
56Stachydrine Ameliorates Cardiac Fibrosis Through Inhibition of Angiotensin II/Transformation Growth Factor β1 Fibrogenic AxisFrontiers in Pharmacology2019.055.988上海中医药大学
57Sodium-Glucose CoTransporter-2 Inhibitor Empagliflozin Ameliorates Sunitinib-Induced Cardiac Dysfunction via Regulation of AMPK-mTOR Signaling Pathway-Mediated AutophagyFrontiers in Pharmacology2021.045.988海军医科大学长征医院
58Bawei Chenxiang Wan Ameliorates Cardiac Hypertrophy by Activating AMPK/PPAR-α Signaling Pathway Improving Energy MetabolismFrontiers in Pharmacology2021.065.988暨大医学院(机器西藏民族大学)
59Xin-Ji-Er-Kang protects heart from ischemia-reperfusion injury by rebalancing lipid metabolisFrontiers in Pharmacology2022.085.988安徽医科大学基础医学院
60Research on the Mechanism and Prevention of Hypertension Caused by Apatinib Through the RhoA/ROCK Signaling Pathway in a Mouse Model of Gastric CancerFrontiers in Cardiovascular Medicine2022.065.846兰州大学第二医院
61Suppression of SMOC2 alleviates myocardial fibrosis via the ILK/p38 pathwayFrontiers in Cardiovascular Medicine2023.035.846武汉大学人民医院
62IL-6/STAT3 Signaling Promotes Cardiac Dysfunction by Upregulating FUNDC1-Dependent Mitochondria-Associated Endoplasmic Reticulum Membranes Formation in Sepsis MiceFrontiers in Cardiovascular Medicine2022.015.846华中科技大学武汉同济医学院
63Activation of cannabinoid receptor 2 attenuates Angiotensin II-induced atrial fibrillation via a potential NOX/CaMKII mechanismFrontiers in Cardiovascular Medicine2022.15.846北方战区总医院
64MicroRNA-194-5p Attenuates Doxorubicin-Induced Cardiomyocyte Apoptosis and Endoplasmic Reticulum Stress by Targeting P21-Activated Kinase 2Frontiers in Cardiovascular Medicine2022.035.846青岛大学基础医学院
65Yes-associated protein contributes to magnesium alloy-derivedinflammation in endothelial cellsRegenerative Biomaterials2022.015.763四川大学国家生物材料工程研究中心
66The biological responses and mechanisms of endothelial cells to magnesium alloyRegenerative Biomaterials2021.055.763四川大学生物材料国家工程研究中心 
67Ultrasound-Targeted Microbubble Destruction Alleviates Immunosuppression Induced by CD71+ Erythroid Progenitor Cells and Promotes PDL-1 Blockade Immunotherapy in the Lewis Lung Cancer ModelFrontiers in Oncology2021.15.738第三军医大学新桥医院
68Preparation of ultrasound contrast agents: The exploration of the structure-echogenicity relationship of contrast agents based on neural network modelFrontiers in Oncology2022.15.738河北医科大学第二医院
69USP38 exacerbates atrial inflammation, fibrosis, and susceptibility to atrial fibrillation after myocardial infarction in miceMol Med2023.11.125.7武汉大学人民医院心内科
70Suxiao Jiuxin Pill attenuates acute myocardial ischemia via regulation of coronary artery toneFrontiers in Pharmacology2023.055.6天津中医药大学中医药研究所
71IR780 Based Sonotherapeutic Nanoparticles to Combat Multidrug-Resistant Bacterial InfectionsFrontiers in Chemistry2022.015.545中南大学湘雅第二医院
72Brain‐Derived Neurotrophic Factor Precursor Contributes to a Proinflammatory Program in Monocytes/Macrophages After Acute Myocardial InfarctionJournal of the American Heart Association2023.055.4中南大学湘雅二医院麻醉科
73Microglia‐Mediated Neuroimmune Response Regulates Cardiac Remodeling After Myocardial InfarctionJournal of the American Heart Association2023.065.4武汉大学人民医院心内科
74Pinocembrin ameliorates arrhythmias in rats with chronic ischaemic heart failureAnnals of Medicine2021.125.348武汉大学人民医院
75MARCH5 restores endothelial cell function against ischaemic/hypoxia injury via Akt/eNOS pathwayJournal of Cellular and Molecular Medicine2021.025.295四川大学华西医院
76D-galactose causes sinoatrial node dysfunction: from phenotype to mechanismAging (Albany NY)2023.11.095.2辽宁中医药大学附属医院
77Cyclovirobuxine D protects against diabetic cardiomyopathy by activating Nrf2-mediated antioxidant responsesScientific Reports2020.044.996贵州医科大学基础医学院
78Sononeoperfusion: a new therapeutic effect to enhance tumour blood perfusion using diagnostic ultrasound and microbubblesCancer Imaging2023.034.9第三军医大学新桥医院
79Salvianolic acid B ameliorates myocardial fibrosis in diabetic cardiomyopathy by deubiquitinating Smad7Chinese Medicine2023.12.104.9贵州医科大学基础医学院
80Ultrasound-mediated microbubbles cavitation enhanced chemotherapy of advanced prostate cancer by increasing the permeability of blood-prostate barrierTranslational Oncology2021.14.803北京大学第三医院泌尿外科
81The Anti-Inflammatory Mediator 17(R)-Resolvin D1 Attenuates Pressure Overload-Induced Cardiac Hypertrophy and FibrosisDrug Design Development and Therapy2023.10.114.8武汉大学人民医院心内科
82Exercise Training Enhances Myocardial Mitophagy and Improves Cardiac Function via Irisin/FNDC5-PINK1/Parkin Pathway in MI MiceBiomedicines2021.064.757陕西师范大学体育学院
83Notopterol Ameliorates Hyperuricemia-Induced Cardiac Dysfunction in MicePharmaceuticals (Basel)2023.034.6华中科技大学同济医学院同济医院心内科
84Effect of diagnostic ultrasound and microbubble-enhanced chemotherapy on metastasis of rabbit VX2 tumorMedical Physics2021.074.506陆军医科大学第二医院新桥医院
85Metabolites and gene expression in the myocardium of fasting rats in an acute hypoxic environmentBMC GENOMICS2023.054.4军事医学科学院北京生物技术研究所
86An Integrative Pharmacology-Based Strategy to Uncover the Mechanism of Zuogui Jiangtang Shuxin Formula in Diabetic Cardiomyopathy Drug Design Development and Therapy2023.014.319湖南中医药大学
87Study on the Application of Super-Resolution Ultrasound for Cerebral Vessel Imaging in Rhesus MonkeysFrontiers in Neurology2021.114.086西北工业大学医学研究所
88Intelligent contour extraction approach for accurate segmentation of medical ultrasound imagesFrontiers in Physiology2023.08.224香港理工大学卫生科技及资讯学系
89Development and validation of risk prediction and neural network models for dilated cardiomyopathy based on WGCNAFront Med (Lausanne).2023.10.53.9中国自贡市第一人民医院
90Toxoplasma gondii Reactivation Aggravating Cardiac Function Impairment in Micepathogens2023.083.7安徽医科大学公共卫生学院卫生
91Ultrasound-Targeted Microbubble Destruction Accelerates Angiogenesis and Ameliorates Left Ventricular Dysfunction after Myocardial Infarction in Mice Ultrasound in Medicine and Biology2021.063.694第三军医大学新桥医院
92Dapagliflozin reduces pulmonary vascular damage and susceptibility to atrial fibrillation in right heart diseaseEsc Heart Failure2023.023.612武汉大学人民医院
93Mettl3 deficiency leads to the upregulation of Cav1.2 and increases arrhythmia susceptibility in miceActa Biochimica et Biophysica Sinica2022.013.511哈尔滨医科大学药学院
94Protective effect of canagliflozin on post-resuscitation myocardial function in a rat model of cardiac arrestIntensive Care Medicine Experimental2023.11.153.5安徽医科大学第二附属医院
95Mechanistic analysis of resveratrol in cardiac hypertrophy by network pharmacology and animal experiments Molecular Medicine Reports2022.093.423齐齐哈尔医科大学
96Circular RNA (circRNA) CDYL Induces Myocardial Regeneration by ceRNA After Myocardial InfarctionMedical Science Monitor2020.063.386青岛大学附属医院
97Ferulic Acid Alleviates Myocardial Ischemia Reperfusion Injury Via Upregulating AMPKα2 Expression-Mediated Ferroptosis DepressionJournal of Cardiovascular Pharmacology2021.123.271南昌大学第二附属医院心胸外科
98Nicotinic Acid Riboside Regulates Nrf-2/P62-Related Oxidative Stress and Autophagy to Attenuate Doxorubicin-Induced Cardiomyocyte InjuryBiomed Research International2022.023.246青岛大学基础医学院附属医院
99The Application of [68Ga]-LABeled FAPI-04 PET/CT for Targeting and Early Detection of Pancreatic Carcinoma in Patient-Derived Orthotopic Xenograft ModelsContrast Media & Molecular Imaging2022.083.009第四军医大学
100Establishment and effect evaluation of a stress cardiomyopathy mouse model induced by different doses of isoprenalineExperimental and Therapeutic Medicine2023.022.751安徽中医药大学
101Naringin attenuates rat myocardial ischemia/reperfusion injury via PI3K/Akt pathway-mediated inhibition of apoptosis, oxidative stress and autophagy Experimental and Therapeutic Medicine2021.082.751湖北中医药大学随州医院
102Xin-Ji-Er-Kang Alleviates Isoproterenol-Induced Myocardial Hypertrophy in Mice through the Nrf2/HO-1 Signaling PathwayEvidence-Based Complementary and Alternative Medicine2022.082.65皖南医学院基础医学院
103CD137 signaling aggravates myocardial ischemia-reperfusion injury by inhibiting mitophagy mediated NLRP3 inflammasome activationJournal of Geriatric Cardiology2023.052.5江苏大学附属医院心内科
104Dapagliflozin attenuates cardiac remodeling and dysfunction in rats with β-adrenergic receptor overactivation through restoring calcium handling and suppressing cardiomyocyte apoptosisDiabetes & Vascular Disease Research2023.08.172.4武汉大学人民医院心内科
105Evaluation of early arterial wall lesions by elastography parameters in spontaneously hypertensive ratsBMC Cardiovasc Disord2023.032.174首都医科大学附属北京友谊医院
106Ultrasound-targeted microbubble destruction promotes myocardial angiogenesis and functional improvements in rat model of diabetic cardiomyopathyBMC Cardiovascular Disorders2021.012.174郑州大学人民医院
107Effects of pregnancy on electrocardiographic, vasovagal tonus index, and echocardiographic variables in horsesVet World2023.08.151.6Mahasarakham大学兽医学院
108Effects of medetomidine on intra-renal arteries resistive and pulsatility indices in clinically normal adult domestic shorthair catsVeterinary Research Forum2018.060.95伊朗德黑兰伊斯兰阿扎德大学
109Up-regulation of Thioredoxin 1 by aerobic exercise training attenuates endoplasmic reticulum stress and cardiomyocyte apoptosis following myocardial infarctionSports Med Health Sci2020.07NF陕西师范大学体育学院


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